Version 5.4
| Bos taurus Gene: CYCS | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-649069.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | CYCS | ||||||||||
| Gene Name | Cytochrome c | ||||||||||
| Synonyms | cytc | ||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Gene | ENSBTAG00000023823 | ||||||||||
| Encoded Proteins |
Cytochrome c
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172115:
This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.[provided by RefSeq, Jul 2010] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 11:98339924-98340241 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | |||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Orphan transporters pathway
Activation of caspases through apoptosome-mediated cleavage pathway
Transcriptional activation of mitochondrial biogenesis pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Cellular responses to stress pathway
Formation of apoptosome pathway
Detoxification of Reactive Oxygen Species pathway
Transmembrane transport of small molecules pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Cytochrome c-mediated apoptotic response pathway
Intrinsic Pathway for Apoptosis pathway
Metabolism pathway
Respiratory electron transport pathway
Release of apoptotic factors from the mitochondria pathway
Mitochondrial biogenesis pathway
Apoptotic factor-mediated response pathway
Apoptosis pathway
Organelle biogenesis and maintenance pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH |
BCR pathway
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| REACTOME |
Activation of caspases through apoptosome-mediated cleavage pathway
Formation of apoptosome pathway
Release of apoptotic factors from the mitochondria pathway
Respiratory electron transport pathway
Cellular responses to stress pathway
Transmembrane transport of small molecules pathway
Organelle biogenesis and maintenance pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Mitochondrial biogenesis pathway
Detoxification of Reactive Oxygen Species pathway
Apoptosis pathway
Orphan transporters pathway
Apoptotic factor-mediated response pathway
Transcriptional activation of mitochondrial biogenesis pathway
Cytochrome c-mediated apoptotic response pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Intrinsic Pathway for Apoptosis pathway
Metabolism pathway
Apoptosis pathway
Organelle biogenesis and maintenance pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Cellular responses to stress pathway
Activation of caspases through apoptosome-mediated cleavage pathway
Orphan transporters pathway
Respiratory electron transport pathway
Detoxification of Reactive Oxygen Species pathway
Metabolism pathway
Cytochrome c-mediated apoptotic response pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Release of apoptotic factors from the mitochondria pathway
Transcriptional activation of mitochondrial biogenesis pathway
Transmembrane transport of small molecules pathway
Formation of apoptosome pathway
Mitochondrial biogenesis pathway
Apoptotic factor-mediated response pathway
Intrinsic Pathway for Apoptosis pathway
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| KEGG |
Colorectal cancer pathway
Apoptosis pathway
Alzheimer's disease pathway
Small cell lung cancer pathway
Sulfur metabolism pathway
p53 signaling pathway pathway
Amyotrophic lateral sclerosis (ALS) pathway
Parkinson's disease pathway
Huntington's disease pathway
Pathways in cancer pathway
Viral myocarditis pathway
Toxoplasmosis pathway
Sulfur metabolism pathway
p53 signaling pathway pathway
Alzheimer's disease pathway
Colorectal cancer pathway
Small cell lung cancer pathway
Apoptosis pathway
Parkinson's disease pathway
Amyotrophic lateral sclerosis (ALS) pathway
Huntington's disease pathway
Pathways in cancer pathway
Viral myocarditis pathway
Toxoplasmosis pathway
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| INOH |
TNFR1 signaling pathway pathway
Fas signaling pathway pathway
TNFR1 signaling pathway pathway
Fas signaling pathway pathway
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| PID NCI |
Ceramide signaling pathway
Caspase Cascade in Apoptosis
mTOR signaling pathway
p75(NTR)-mediated signaling
HIV-1 Nef: Negative effector of Fas and TNF-alpha
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| Cross-References | |||||||||||
| SwissProt | P62894 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 510767 | ||||||||||
| UniGene | |||||||||||
| RefSeq | |||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | BC105397 | ||||||||||
| GenPept | AAI05398 | ||||||||||
| RNA Seq Atlas | 100850794 510767 | ||||||||||