Version 5.4
Homo sapiens Gene: SLC35C2
Summary
InnateDB Gene IDBG-79031.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC35C2
Gene Name solute carrier family 35, member C2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000080189
Encoded Proteins
IDBP-79033
solute carrier family 35, member C2
IDBP-79035
solute carrier family 35, member C2
IDBP-79039
solute carrier family 35, member C2
IDBP-79041
solute carrier family 35, member C2
IDBP-377154
solute carrier family 35, member C2
IDBP-377156
solute carrier family 35, member C2
IDBP-590106
solute carrier family 35, member C2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Oxygenation levels play an important role in the regulation of cellular invasiveness which occurs during early implantation when the trophoblast cells invade the uterus as well as during tumour progression and metastasis. This gene, which is regulated by oxygen tension, is induced in hypoxic trophoblast cells and is overexpressed in ovarian cancer. Two protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:46345980-46364458
Strand Reverse strand
Band q13.12
Transcripts
ENST00000317734 ENSP00000318960
ENST00000372230 ENSP00000361304
ENST00000372227 ENSP00000361301
ENST00000243896 ENSP00000243896
ENST00000420518 ENSP00000397142
ENST00000424568 ENSP00000415736
ENST00000493599
ENST00000480329
ENST00000487729
ENST00000484318
ENST00000481809
ENST00000484188
ENST00000543605 ENSP00000439974
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
GO:0010629 negative regulation of gene expression
GO:0036065 fucosylation
GO:0036066 protein O-linked fucosylation
GO:0045747 positive regulation of Notch signaling pathway
GO:0055085 transmembrane transport
Cellular Component
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005801 cis-Golgi network
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017664
View Gene Order
ENSBTAG00000003635
Not yet available
Cross-References
SwissProt Q9NQQ7
TrEMBL
UniProt Splice Variant
Entrez Gene 51006
UniGene Hs.742147
RefSeq NM_173179 NM_001281457 NM_001281458 NM_001281459 NM_001281460 NM_015945 NM_173073 XM_005260414
HUGO HGNC:17117
OMIM
CCDS CCDS13396 CCDS13397 CCDS63292
HPRD 15371
IMGT
EMBL AF132949 AF455052 AL133227 BC014191 BC021138 BC025277 CH471077
GenPept AAD27724 AAH14191 AAH21138 AAH25277 AAL59605 CAC00659 CAI40552 EAW75747 EAW75748 EAW75750 EAW75751 EAW75752
RNA Seq Atlas 51006

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca