Version 5.4
Homo sapiens Gene: ATG9A
Summary
InnateDB Gene IDBG-81394.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATG9A
Gene Name autophagy related 9A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198925
Encoded Proteins
IDBP-81396
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-236805
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-293018
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-293014
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-293015
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389010
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389011
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389012
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389013
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389014
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389015
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389016
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389017
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389018
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389019
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389020
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389021
ATG9 autophagy related 9 homolog A (S. cerevisiae)
IDBP-389022
ATG9 autophagy related 9 homolog A (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 19926846
ATG9A is an essential autophagy protein that functions as a regulator of innate immunity following double stranded DNA stimulation by controlling dsDNA-driven dynamic translocation of stimulator of IFN genes (STING), aka TMEM173, and TBK1.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:219209772-219229717
Strand Reverse strand
Band q35
Transcripts
ENST00000361242 ENSP00000355173
ENST00000396761 ENSP00000379983
ENST00000409618 ENSP00000386710
ENST00000409033 ENSP00000386482
ENST00000409422 ENSP00000386535
ENST00000446716 ENSP00000398528
ENST00000429920 ENSP00000400234
ENST00000431715 ENSP00000396404
ENST00000436856 ENSP00000401530
ENST00000457841 ENSP00000404750
ENST00000428226 ENSP00000409164
ENST00000412355 ENSP00000393708
ENST00000432520 ENSP00000406785
ENST00000439812 ENSP00000413569
ENST00000456708 ENSP00000390704
ENST00000455079 ENSP00000398425
ENST00000443140 ENSP00000416435
ENST00000434939 ENSP00000394345
ENST00000475339
ENST00000466217
ENST00000486766
ENST00000488833
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 13 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015002 heme-copper terminal oxidase activity
Biological Process
GO:0000045 autophagic vacuole assembly
GO:0000422 mitochondrion degradation
GO:0006914 autophagy
GO:0015031 protein transport
GO:0034497 protein localization to pre-autophagosomal structure
GO:0034727 piecemeal microautophagy of nucleus
GO:0044805 late nucleophagy
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0000407 pre-autophagosomal structure
GO:0000421 autophagic vacuole membrane
GO:0005768 endosome
GO:0005770 late endosome
GO:0005776 autophagic vacuole
GO:0005789 endoplasmic reticulum membrane
GO:0005802 trans-Golgi network
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031410 cytoplasmic vesicle
GO:0031902 late endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033124
View Gene Order
ENSBTAG00000020608
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.323363 Hs.603397
RefSeq NM_001077198 NM_024085
HUGO
OMIM
CCDS CCDS42820
HPRD 07979
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca