Homo sapiens Gene: BRDT
Summary
InnateDB Gene IDBG-100249.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRDT
Gene Name bromodomain, testis-specific
Synonyms BRD6; CT9;
Species Homo sapiens
Ensembl Gene ENSG00000137948
Encoded Proteins
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
bromodomain, testis-specific
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:91949371-92014426
Strand Forward strand
Band p22.1
Transcripts
ENST00000362005 ENSP00000354568
ENST00000370389 ENSP00000359416
ENST00000355011 ENSP00000400199
ENST00000399546 ENSP00000387822
ENST00000394530 ENSP00000378038
ENST00000402388 ENSP00000384051
ENST00000423434 ENSP00000396351
ENST00000440509 ENSP00000416714
ENST00000427104 ENSP00000400002
ENST00000449584 ENSP00000408625
ENST00000426141 ENSP00000404969
ENST00000448194 ENSP00000410587
ENST00000450792 ENSP00000414349
ENST00000457265 ENSP00000408138
ENST00000470955
ENST00000476711
ENST00000461218
ENST00000484833
ENST00000484781
ENST00000548992 ENSP00000447394
ENST00000552654 ENSP00000446599
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0042393 histone binding
GO:0070577 lysine-acetylated histone binding
Biological Process
GO:0001207 histone displacement
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006397 mRNA processing
GO:0007140 male meiosis
GO:0007141 male meiosis I
GO:0007283 spermatogenesis
GO:0008380 RNA splicing
GO:0030154 cell differentiation
GO:0043484 regulation of RNA splicing
GO:0051039 positive regulation of transcription during meiosis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL F8W0H2
UniProt Splice Variant
Entrez Gene 676
UniGene Hs.482520 Hs.739345
RefSeq NM_001242805 NM_001242806 NM_001242807 NM_001242808 NM_001242810 NM_001726 NM_207189 XM_006710858
HUGO HGNC:1105
OMIM 602144
CCDS CCDS55615 CCDS55616 CCDS72820 CCDS735
HPRD 03684
IMGT
EMBL AC114486
GenPept
RNA Seq Atlas 676