Homo sapiens Gene: RTCA
Summary
InnateDB Gene IDBG-100504.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RTCA
Gene Name RNA 3'-terminal phosphate cyclase
Synonyms RPC; RTC1; RTCD1
Species Homo sapiens
Ensembl Gene ENSG00000137996
Encoded Proteins
RNA terminal phosphate cyclase domain 1
RNA terminal phosphate cyclase domain 1
RNA terminal phosphate cyclase domain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the RNA 3'-phosphate cyclase family. The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3'-phosphate of RNA substrates to a 2',3'-cyclic phosphodiester. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
This gene encodes a member of the RNA 3\'-phosphate cyclase family. The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3\'-phosphate of RNA substrates to a 2\',3\'-cyclic phosphodiester. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:100266207-100292769
Strand Forward strand
Band p21.2
Transcripts
ENST00000370128 ENSP00000359146
ENST00000260563 ENSP00000260563
ENST00000370126 ENSP00000359144
ENST00000498617
ENST00000483474
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003824 catalytic activity
GO:0003963 RNA-3'-phosphate cyclase activity
GO:0005524 ATP binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001130841 NM_003729 XM_005271299
HUGO
OMIM
CCDS CCDS44178 CCDS768
HPRD 15280
IMGT
EMBL
GenPept
RNA Seq Atlas