Version 5.4
Homo sapiens Gene: CHTOP
Summary
InnateDB Gene IDBG-102750.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHTOP
Gene Name chromatin target of PRMT1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000160679
Encoded Proteins
IDBP-102752
chromatin target of PRMT1
IDBP-102754
chromatin target of PRMT1
IDBP-102756
chromatin target of PRMT1
IDBP-102758
chromatin target of PRMT1
IDBP-293426
chromatin target of PRMT1
IDBP-808628
chromatin target of PRMT1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a small nuclear protein that is characterized by a arginine and glycine rich region. The encoded protein may be involved in cell cycle progression. This protein interacts with protein arginine methyltransferases and plays a role in the activation of estradiol-dependent transcription. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:153633982-153646306
Strand Forward strand
Band q21.3
Transcripts
ENST00000368694 ENSP00000357683
ENST00000368690 ENSP00000357679
ENST00000368687 ENSP00000357676
ENST00000368686 ENSP00000357675
ENST00000403433 ENSP00000385228
ENST00000495554
ENST00000614256 ENSP00000484038
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006406 mRNA export from nucleus
GO:0032781 positive regulation of ATPase activity
GO:0051096 positive regulation of helicase activity
Cellular Component
GO:0000346 transcription export complex
GO:0005730 nucleolus
GO:0016607 nuclear speck
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000001017
View Gene Order
ENSBTAG00000005166
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.728799
RefSeq NM_001206612 NM_001244664 NM_015607
HUGO
OMIM
CCDS CCDS1048 CCDS72917 CCDS72918
HPRD 13163
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca