Homo sapiens Gene: GNG4
Summary
InnateDB Gene IDBG-107558.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GNG4
Gene Name guanine nucleotide binding protein (G protein), gamma 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168243
Encoded Proteins
guanine nucleotide binding protein (G protein), gamma 4
guanine nucleotide binding protein (G protein), gamma 4
guanine nucleotide binding protein (G protein), gamma 4
guanine nucleotide binding protein (G protein), gamma 4
guanine nucleotide binding protein (G protein), gamma 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:235547687-235650754
Strand Reverse strand
Band q42.3
Transcripts
ENST00000366598 ENSP00000355557
ENST00000366597 ENSP00000355556
ENST00000391854 ENSP00000375727
ENST00000450593 ENSP00000398629
ENST00000484517 ENSP00000482192
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
Biological Process
GO:0006112 energy reserve metabolic process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007268 synaptic transmission
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0030308 negative regulation of cell growth
GO:0044281 small molecule metabolic process
GO:0071377 cellular response to glucagon stimulus
Cellular Component
GO:0005834 heterotrimeric G-protein complex
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
G alpha (s) signalling events pathway
Integration of energy metabolism pathway
ADP signalling through P2Y purinoceptor 12 pathway
Presynaptic function of Kainate receptors pathway
Transmembrane transport of small molecules pathway
G alpha (12/13) signalling events pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Ca2+ pathway pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G alpha (q) signalling events pathway
beta-catenin independent WNT signaling pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Signaling by Wnt pathway
Neuronal System pathway
Signaling by GPCR pathway
Prostacyclin signalling through prostacyclin receptor pathway
GABA receptor activation pathway
Glucagon signaling in metabolic regulation pathway
G protein gated Potassium channels pathway
Platelet activation, signaling and aggregation pathway
G-protein beta:gamma signalling pathway
Opioid Signalling pathway
Activation of GABAB receptors pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (i) signalling events pathway
Glucagon-type ligand receptors pathway
G-protein activation pathway
Inwardly rectifying K+ channels pathway
Activation of Kainate Receptors upon glutamate binding pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Platelet homeostasis pathway
G alpha (z) signalling events pathway
Potassium Channels pathway
GABA B receptor activation pathway
Thromboxane signalling through TP receptor pathway
Transmission across Chemical Synapses pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
ADP signalling through P2Y purinoceptor 1 pathway
G beta:gamma signalling through PLC beta pathway
GPCR ligand binding pathway
Regulation of insulin secretion pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
G beta:gamma signalling through PI3Kgamma pathway
Signal amplification pathway
Activation of G protein gated Potassium channels pathway
Class B/2 (Secretin family receptors) pathway
Aquaporin-mediated transport pathway
Hemostasis pathway
KEGG
Chemokine signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P50150
TrEMBL B1APZ0
UniProt Splice Variant
Entrez Gene 2786
UniGene Hs.159711
RefSeq NM_001098722 XM_006711761 XM_006711762 NM_004485 NM_001098721
HUGO HGNC:4407
OMIM 604388
CCDS CCDS1607
HPRD 11978
IMGT
EMBL AF493872 AK311781 BC022485 CH471098 U31382
GenPept AAC50204 AAH22485 AAM12586 BAG34724 EAW70030 EAW70031
RNA Seq Atlas 2786