Mus musculus Gene: Stmn2
Summary
InnateDB Gene IDBG-130673.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stmn2
Gene Name stathmin-like 2
Synonyms AI159727; SCG10; Scgn10; Stmb2;
Species Mus musculus
Ensembl Gene ENSMUSG00000027500
Encoded Proteins
stathmin-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104435:
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down\'s syndrome and Alzheimer\'s disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:8509527-8561604
Strand Forward strand
Band A1
Transcripts
ENSMUST00000029002 ENSMUSP00000029002
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0007026 negative regulation of microtubule depolymerization
GO:0010976 positive regulation of neuron projection development
GO:0010977 negative regulation of neuron projection development
GO:0031110 regulation of microtubule polymerization or depolymerization
GO:0031115 negative regulation of microtubule polymerization
GO:0031117 positive regulation of microtubule depolymerization
GO:1990090 cellular response to nerve growth factor stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0030027 lamellipodium
GO:0030424 axon
GO:0030426 growth cone
GO:0031982 vesicle
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt P55821
TrEMBL Q545S4
UniProt Splice Variant
Entrez Gene 20257
UniGene Mm.400075 Mm.409993
RefSeq NM_025285
OMIM
CCDS CCDS17231
HPRD
IMGT
MGI ID MGI:98241
MGI Symbol Stmn2
EMBL AK003659 AK149212 BC026538 CH466577 L20259 L20260 L20261 L20262 L20263
GenPept AAH26538 BAB22921 BAE28766 EDL05200
RNA Seq Atlas 20257