InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: S1pr2

Summary

InnateDB Gene

IDBG-138519.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

S1pr2

Gene Name

sphingosine-1-phosphate receptor 2

Synonyms

1100001A16Rik; Edg5; Gpcr13; H218; LPb2; S1P2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000043895

Encoded Proteins

IDBP-138521

sphingosine-1-phosphate receptor 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000267534:
This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:20965952-20976793

Strand

Reverse strand

Band

Transcripts

ENSMUST00000054197

ENSMUSP00000053394

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001664	G-protein coupled receptor binding
GO:0004930	G-protein coupled receptor activity
GO:0005178	integrin binding
GO:0038036	sphingosine-1-phosphate receptor activity

Biological Process

GO:0003376	sphingosine-1-phosphate signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0090394	negative regulation of excitatory postsynaptic membrane potential
GO:1903142	positive regulation of establishment of endothelial barrier