Mus musculus Gene: Serpind1
Summary
InnateDB Gene IDBG-138819.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpind1
Gene Name serine (or cysteine) peptidase inhibitor, clade D, member 1
Synonyms AA985900; AI303446; Hcf2; HCII;
Species Mus musculus
Ensembl Gene ENSMUSG00000022766
Encoded Proteins
serine (or cysteine) peptidase inhibitor, clade D, member 1
serine (or cysteine) peptidase inhibitor, clade D, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099937:
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:17331371-17343575
Strand Forward strand
Band A3
Transcripts
ENSMUST00000023450 ENSMUSP00000023450
ENSMUST00000161034 ENSMUSP00000125507
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0008201 heparin binding
Biological Process
GO:0007596 blood coagulation
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Hemostasis pathway
Intrinsic Pathway pathway
Formation of Fibrin Clot (Clotting Cascade) pathway
Common Pathway pathway
KEGG
Complement and coagulation cascades pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Formation of Fibrin Clot (Clotting Cascade) pathway
Intrinsic Pathway pathway
Common Pathway pathway
Hemostasis pathway
KEGG
Complement and coagulation cascades pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P49182
TrEMBL
UniProt Splice Variant
Entrez Gene 15160
UniGene Mm.6609
RefSeq XM_006521796 NM_008223
OMIM
CCDS CCDS28000
HPRD
IMGT
MGI ID MGI:96051
MGI Symbol Serpind1
EMBL BC034543 U07425
GenPept AAA18452 AAH34543
RNA Seq Atlas 15160