Homo sapiens Gene: ESCO1
Summary
InnateDB Gene IDBG-1402.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ESCO1
Gene Name establishment of cohesion 1 homolog 1 (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141446
Encoded Proteins
establishment of cohesion 1 homolog 1 (S. cerevisiae)
establishment of cohesion 1 homolog 1 (S. cerevisiae)
establishment of sister chromatid cohesion N-acetyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:21529281-21600884
Strand Reverse strand
Band q11.2
Transcripts
ENST00000383276 ENSP00000372763
ENST00000269214 ENSP00000269214
ENST00000580101
ENST00000622333 ENSP00000484873
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016746 transferase activity, transferring acyl groups
GO:0046872 metal ion binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006275 regulation of DNA replication
GO:0007062 sister chromatid cohesion
GO:0034421 post-translational protein acetylation
Cellular Component
GO:0000785 chromatin
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Establishment of Sister Chromatid Cohesion pathway
S Phase pathway
Cell Cycle pathway
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.464733 Hs.621074
RefSeq NM_052911 XM_006722379
HUGO
OMIM
CCDS CCDS32800
HPRD 16868
IMGT
EMBL
GenPept
RNA Seq Atlas