Version 5.4
Homo sapiens Gene: ESCO1
Summary
InnateDB Gene IDBG-1402.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ESCO1
Gene Name establishment of cohesion 1 homolog 1 (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141446
Encoded Proteins
IDBP-1404
establishment of cohesion 1 homolog 1 (S. cerevisiae)
IDBP-1406
establishment of cohesion 1 homolog 1 (S. cerevisiae)
IDBP-812786
establishment of sister chromatid cohesion N-acetyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:21529281-21600884
Strand Reverse strand
Band q11.2
Transcripts
ENST00000383276 ENSP00000372763
ENST00000269214 ENSP00000269214
ENST00000580101
ENST00000622333 ENSP00000484873
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016746 transferase activity, transferring acyl groups
GO:0046872 metal ion binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006275 regulation of DNA replication
GO:0007062 sister chromatid cohesion
GO:0034421 post-translational protein acetylation
Cellular Component
GO:0000785 chromatin
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024293
View Gene Order
ENSBTAG00000017597
Not yet available
Pathways
NETPATH
REACTOME
REACT_150266
Establishment of Sister Chromatid Cohesion pathway
REACT_899
S Phase pathway
REACT_115566
Cell Cycle pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.464733 Hs.621074
RefSeq NM_052911 XM_006722379
HUGO
OMIM
CCDS CCDS32800
HPRD 16868
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca