Mus musculus Gene: Fez1
Summary
InnateDB Gene IDBG-149600.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fez1
Gene Name fasciculation and elongation protein zeta 1 (zygin I)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032118
Encoded Proteins
fasciculation and elongation protein zeta 1 (zygin I)
fasciculation and elongation protein zeta 1 (zygin I)
fasciculation and elongation protein zeta 1 (zygin I)
fasciculation and elongation protein zeta 1 (zygin I)
fasciculation and elongation protein zeta 1 (zygin I)
fasciculation and elongation protein zeta 1 (zygin I)
fasciculation and elongation protein zeta 1 (zygin I)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149557:
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:36821939-36878924
Strand Forward strand
Band A4
Transcripts
ENSMUST00000034630 ENSMUSP00000034630
ENSMUST00000162633 ENSMUSP00000124634
ENSMUST00000161500 ENSMUSP00000123762
ENSMUST00000160041 ENSMUSP00000124648
ENSMUST00000162235 ENSMUSP00000124185
ENSMUST00000159137
ENSMUST00000161978 ENSMUSP00000125475
ENSMUST00000163816 ENSMUSP00000126072
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 54 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 54 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0043015 gamma-tubulin binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0006810 transport
GO:0010976 positive regulation of neuron projection development
GO:0045666 positive regulation of neuron differentiation
GO:0051654 establishment of mitochondrion localization
GO:0071363 cellular response to growth factor stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0015630 microtubule cytoskeleton
GO:0030424 axon
GO:0030425 dendrite
GO:0042995 cell projection
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL E0CXY1 E0CYY9
UniProt Splice Variant
Entrez Gene 235180
UniGene Mm.5264
RefSeq NM_183171 XM_006510227
OMIM
CCDS CCDS40581
HPRD
IMGT
MGI ID MGI:2670976
MGI Symbol Fez1
EMBL CT009699 CT955982
GenPept
RNA Seq Atlas 235180