Homo sapiens Gene: RBPMS
Summary
InnateDB Gene IDBG-15727.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBPMS
Gene Name RNA binding protein with multiple splicing
Synonyms HERMES;
Species Homo sapiens
Ensembl Gene ENSG00000157110
Encoded Proteins
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
RNA binding protein with multiple splicing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the RRM family of RNA-binding proteins. The RRM domain is between 80-100 amino acids in length and family members contain one to four copies of the domain. The RRM domain consists of two short stretches of conserved sequence called RNP1 and RNP2, as well as a few highly conserved hydrophobic residues. The protein encoded by this gene has a single, putative RRM domain in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:30384479-30572261
Strand Forward strand
Band p12
Transcripts
ENST00000320203 ENSP00000318102
ENST00000287771 ENSP00000287771
ENST00000339877 ENSP00000340176
ENST00000397323 ENSP00000380486
ENST00000517860 ENSP00000428675
ENST00000520161 ENSP00000427896
ENST00000523115 ENSP00000429086
ENST00000519647 ENSP00000430342
ENST00000521816
ENST00000520191 ENSP00000430638
ENST00000523717
ENST00000522708
ENST00000519359 ENSP00000430370
ENST00000522694 ENSP00000430893
ENST00000522099
ENST00000521370
ENST00000523104
ENST00000519657
ENST00000520916
ENST00000520971
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 69 [view]
Protein-Protein 69 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008143 poly(A) binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006396 RNA processing
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0060391 positive regulation of SMAD protein import into nucleus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q93062
TrEMBL B4E3T4 E5RFP4 E5RJ31 E5RJD7 H0YC46
UniProt Splice Variant
Entrez Gene 11030
UniGene Hs.613171
RefSeq NM_001008710 NM_001008711 NM_001008712 NM_006867 XM_006716277 XM_006716278
HUGO HGNC:19097
OMIM 601558
CCDS CCDS34875 CCDS34876 CCDS6077
HPRD
IMGT
EMBL AC011204 AC102945 AC109329 AK304858 BC003608 CH471080 D84107 D84108 D84109 D84110 D84111
GenPept AAH03608 BAA12225 BAA12226 BAA12227 BAA12228 BAA12229 BAG65596 EAW63451 EAW63453 EAW63460
RNA Seq Atlas 11030