Mus musculus Gene: Cyp26a1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-162003.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | Cyp26a1 | ||||||||||||||||||
Gene Name | cytochrome P450, family 26, subfamily a, polypeptide 1 | ||||||||||||||||||
Synonyms | Cyp26; P450RA; P450RAI; RAH | ||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||
Ensembl Gene | ENSMUSG00000024987 | ||||||||||||||||||
Encoded Proteins |
cytochrome P450, family 26, subfamily a, polypeptide 1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095596:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 19:37697808-37701528 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | C2 | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Cytochrome P450 - arranged by substrate type pathway
Phase 1 - Functionalization of compounds pathway
Vitamins pathway
Metabolism pathway
Biological oxidations pathway
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KEGG |
Retinol metabolism pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Vitamins pathway
Cytochrome P450 - arranged by substrate type pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
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KEGG |
Retinol metabolism pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | O55127 | ||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 13082 | ||||||||||||||||||
UniGene | Mm.42230 | ||||||||||||||||||
RefSeq | NM_007811 | ||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS29780 | ||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
MGI ID | MGI:1096359 | ||||||||||||||||||
MGI Symbol | Cyp26a1 | ||||||||||||||||||
EMBL | AF115769 BC012673 Y12657 | ||||||||||||||||||
GenPept | AAD17217 AAH12673 CAA73206 | ||||||||||||||||||
RNA Seq Atlas | 13082 | ||||||||||||||||||