Version 5.4
Mus musculus Gene: Igfbp2
Summary
InnateDB Gene IDBG-166043.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Igfbp2
Gene Name insulin-like growth factor binding protein 2
Synonyms AI255832; IBP-2; Igfbp-2; mIGFBP-2
Species Mus musculus
Ensembl Gene ENSMUSG00000039323
Encoded Proteins
IDBP-166045
insulin-like growth factor binding protein 2
IDBP-401103
insulin-like growth factor binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115457:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:72824503-72852474
Strand Forward strand
Band C3
Transcripts
ENSMUST00000047328 ENSMUSP00000046610
ENSMUST00000120564 ENSMUSP00000112706
ENSMUST00000155703
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0031994 insulin-like growth factor I binding
GO:0031995 insulin-like growth factor II binding
Biological Process
GO:0001558 regulation of cell growth
GO:0007165 signal transduction
GO:0007565 female pregnancy
GO:0007568 aging
GO:0007584 response to nutrient
GO:0009612 response to mechanical stimulus
GO:0010226 response to lithium ion
GO:0032355 response to estradiol
GO:0032526 response to retinoic acid
GO:0032870 cellular response to hormone stimulus
GO:0042104 positive regulation of activated T cell proliferation
GO:0042493 response to drug
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway
GO:0043627 response to estrogen
GO:0048545 response to steroid hormone
GO:0051384 response to glucocorticoid
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0016324 apical plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000115457
View Gene Order
ENSBTAG00000005596
Not yet available
Pathways
NETPATH
REACTOME
REACT_247926
Metabolism of proteins pathway
REACT_235886
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15428
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
INOH website
IGF1 signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_008342 XM_006495707
OMIM
CCDS CCDS15036
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca