Mus musculus Gene: Vdac1
Summary
InnateDB Gene IDBG-171107.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vdac1
Gene Name voltage-dependent anion channel 1
Synonyms AL033343; Vdac5;
Species Mus musculus
Ensembl Gene ENSMUSG00000020402
Encoded Proteins
voltage-dependent anion channel 1
voltage-dependent anion channel 1
voltage-dependent anion channel 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213585:
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:52360860-52389397
Strand Forward strand
Band B1.3
Transcripts
ENSMUST00000102758 ENSMUSP00000099819
ENSMUST00000020673 ENSMUSP00000020673
ENSMUST00000125694 ENSMUSP00000116919
ENSMUST00000157052
ENSMUST00000153339
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 72 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 72 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0008308 voltage-gated anion channel activity
GO:0015288 porin activity
Biological Process
GO:0001662 behavioral fear response
GO:0006820 anion transport
GO:0006915 apoptotic process
GO:0007268 synaptic transmission
GO:0007270 neuron-neuron synaptic transmission
GO:0007612 learning
GO:0030855 epithelial cell differentiation
GO:0044070 regulation of anion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0042645 mitochondrial nucleoid
GO:0046930 pore complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Metabolism of proteins pathway
Mitochondrial protein import pathway
KEGG
Calcium signaling pathway pathway
Parkinson's disease pathway
Huntington's disease pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of proteins pathway
Mitochondrial protein import pathway
Mitochondrial protein import pathway
Metabolism of proteins pathway
KEGG
Calcium signaling pathway pathway
Parkinson's disease pathway
Huntington's disease pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q60932
TrEMBL
UniProt Splice Variant
Entrez Gene 22333
UniGene Mm.3555
RefSeq NM_011694
OMIM
CCDS CCDS24671
HPRD
IMGT
MGI ID MGI:106919
MGI Symbol Vdac1
EMBL AK168672 AK169160 AK169282 AK169354 AK169671 AL645589 BC092257 U30840
GenPept AAB47777 AAH92257 BAE40522 BAE40939 BAE41040 BAE41103 BAE41292 CAI24939 CAM19812
RNA Seq Atlas 22333