Version 5.4
Mus musculus Gene: Psd
Summary
InnateDB Gene IDBG-172695.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Psd
Gene Name pleckstrin and Sec7 domain containing
Synonyms 1110007H17Rik; A930015K15; Efa6; Efa6a; mKIAA2011; Psdl
Species Mus musculus
Ensembl Gene ENSMUSG00000037126
Encoded Proteins
IDBP-172697
pleckstrin and Sec7 domain containing
IDBP-172699
pleckstrin and Sec7 domain containing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000059915:
This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:46312087-46327156
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000041391 ENSMUSP00000039728
ENSMUST00000096029 ENSMUSP00000093729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005543 phospholipid binding
Biological Process
GO:0030182 neuron differentiation
GO:0032012 regulation of ARF protein signal transduction
GO:0043087 regulation of GTPase activity
Cellular Component
GO:0001726 ruffle
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000059915
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt Q5DTT2
TrEMBL
UniProt Splice Variant
Entrez Gene 73728
UniGene Mm.487512
RefSeq NM_028627 XM_006527386 XM_006527387 XM_006527388 XM_006527389 XM_006527390 XM_006527391 XM_006527392
OMIM
CCDS CCDS29875
HPRD
IMGT
MGI ID MGI:1920978
MGI Symbol Psd
EMBL AC114539 AK158851 AK220438 BC058352 BC138652 BC145352
GenPept AAH58352 AAI38653 AAI45353 BAD90268 BAE34694
RNA Seq Atlas 73728

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca