Version 5.4
Mus musculus Gene: Nudt14
Summary
InnateDB Gene IDBG-175408.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nudt14
Gene Name nudix (nucleoside diphosphate linked moiety X)-type motif 14
Synonyms 1110030M18Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000002804
Encoded Proteins
IDBP-175410
nudix (nucleoside diphosphate linked moiety X)-type motif 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183828:
UDP-glucose (UDPG) acts as the sugar donor in numerous glycosylation reactions, including those involved in the production of glycogen. NUDT14 is a UDPG pyrophosphatase (EC 3.6.1.45) that hydrolyzes UDPG to produce glucose 1-phosphate and UMP (Yagi et al., 2003 [PubMed 12429023]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:112934733-112942118
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000002881 ENSMUSP00000002881
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008768 UDP-sugar diphosphatase activity
GO:0016787 hydrolase activity
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0046872 metal ion binding
GO:0047631 ADP-ribose diphosphatase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000183828
View Gene Order
ENSBTAG00000048010
Not yet available
Cross-References
SwissProt Q9D142
TrEMBL
UniProt Splice Variant
Entrez Gene 66174
UniGene
RefSeq NM_025399
OMIM
CCDS CCDS26201
HPRD
IMGT
MGI ID MGI:1913424
MGI Symbol Nudt14
EMBL AK003991 AK013174 BC025444
GenPept AAH25444 BAB23110 BAB28691
RNA Seq Atlas 66174

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca