|Mus musculus Gene: Capn10|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||calpain 10|
|Synonyms||AW049679; Capn8; mKIAA1845;|
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142330:
Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq, Sep 2010]
|Genomic Location||Chromosome 1:92934376-92947941|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|RNA Seq Atlas|