Version 5.4
| Mus musculus Gene: Cds1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-183920.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Cds1 | ||||||||
| Gene Name | CDP-diacylglycerol synthase 1 | ||||||||
| Synonyms | 4833409J18Rik; AI314024; AW125888 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000029330 | ||||||||
| Encoded Proteins |
CDP-diacylglycerol synthase 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163624:
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 5:101765130-101823858 | ||||||||
| Strand | Forward strand | ||||||||
| Band | E4 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of PI pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
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| KEGG |
Glycerophospholipid metabolism pathway
Phosphatidylinositol signaling system pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of PI pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
Metabolism pathway
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| KEGG |
Glycerophospholipid metabolism pathway
Phosphatidylinositol signaling system pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | P98191 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 74596 | ||||||||
| UniGene | Mm.46764 | ||||||||
| RefSeq | NM_173370 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS19472 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1921846 | ||||||||
| MGI Symbol | Cds1 | ||||||||
| EMBL | AF533367 BC055292 | ||||||||
| GenPept | AAH55292 AAO16167 | ||||||||
| RNA Seq Atlas | 74596 | ||||||||