Version 5.4
Mus musculus Gene: Gm10094
Summary
InnateDB Gene IDBG-184568.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gm10094
Gene Name predicted gene 10094
Synonyms C530046K05Rik; D11Ertd539e; EMegR4; Sinbp1
Species Mus musculus
Ensembl Gene ENSMUSG00000061104
Encoded Proteins
IDBP-184570
predicted gene 10094
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This intronless gene is highly similar to the multi-exon Sap18 gene on chromosome 14, whose product functions in transcriptional repression as a component of the Sin3 histone deacetylase complex. This gene may possibly be a Sap18 pseudogene, but it is represented as protein-coding because it appears to be transcribed and has an intact ORF that would result in a protein that is 100% identical to the Sap18 protein. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:95825354-95826133
Strand Forward strand
Band D1
Transcripts
ENSMUST00000074053 ENSMUSP00000073697
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 104 interaction(s) predicted by orthology.
Predicted by orthology
Total 104 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0043065 positive regulation of apoptotic process
GO:0048025 negative regulation of mRNA splicing, via spliceosome
Cellular Component
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0061574 ASAP complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000150459
View Gene Order
ENSBTAG00000018631
Not yet available
Pathways
NETPATH
REACTOME
REACT_200794
Mus musculus biological processes pathway
REACT_200667
NoRC negatively regulates rRNA expression pathway
REACT_218274
Chromatin organization pathway
REACT_214440
NoRC negatively regulates rRNA expression pathway
REACT_202766
Chromatin modifying enzymes pathway
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_233572
Gene Expression pathway
REACT_207809
Negative epigenetic regulation of rRNA expression pathway
REACT_257106
HDACs deacetylate histones pathway
KEGG
mmu03013
RNA transport pathway
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_10
Hedgehog pathway
REACTOME
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_200856
NoRC negatively regulates rRNA expression pathway
REACT_228222
HDACs deacetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_71
Gene Expression pathway
REACT_200834
Negative epigenetic regulation of rRNA expression pathway
REACT_213048
Epigenetic regulation of gene expression pathway
REACT_226022
Gene Expression pathway
REACT_207632
Chromatin organization pathway
REACT_248114
HDACs deacetylate histones pathway
REACT_214253
NoRC negatively regulates rRNA expression pathway
REACT_215001
Negative epigenetic regulation of rRNA expression pathway
REACT_227044
Chromatin modifying enzymes pathway
KEGG
hsa03013
RNA transport pathway
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
hdac_classi_pathway
Signaling events mediated by HDAC Class I
smad2_3nuclearpathway
Regulation of nuclear SMAD2/3 signaling
hedgehog_glipathway
Hedgehog signaling events mediated by Gli proteins
telomerasepathway
Regulation of Telomerase
Cross-References
SwissProt O55128
TrEMBL D3YY73 D3Z2N9 E9Q317 Q4FZH3
UniProt Splice Variant
Entrez Gene 20220
UniGene
RefSeq NM_001142441
OMIM
CCDS CCDS52642
HPRD
IMGT
MGI ID MGI:3704317
MGI Symbol Gm10094
EMBL AC119813 AC127300 AK005189 AK006647 AK085992 AK133619 AK144904 AK146928 BC006625 BC099480 CH466525 CH466535 Z97062
GenPept AAH06625 AAH99480 BAB23871 BAB24687 BAC39588 BAE21751 BAE26125 BAE27539 CAB09797 EDL11186 EDL36164
RNA Seq Atlas 100041953 20220

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca