Mus musculus Gene: Alkbh2 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-192205.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Alkbh2 | ||||||||||||
Gene Name | alkB, alkylation repair homolog 2 (E. coli) | ||||||||||||
Synonyms | |||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000044339 | ||||||||||||
Encoded Proteins |
alkB, alkylation repair homolog 2 (E. coli)
alkB, alkylation repair homolog 2 (E. coli)
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189046:
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 5:114123926-114128218 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | F | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Reversal of Alkylation Damage By DNA Dioxygenases pathway
ABH2 mediated Reversal of Alkylation Damage pathway
DNA Repair pathway
DNA Damage Reversal pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
ABH2 mediated Reversal of Alkylation Damage pathway
DNA Damage Reversal pathway
Reversal of Alkylation Damage By DNA Dioxygenases pathway
DNA Repair pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Mm.332593 | ||||||||||||
RefSeq | NM_175016 XM_006530289 XM_006530290 XM_006530292 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS19559 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | |||||||||||||
MGI Symbol | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||