Mus musculus Gene: Flot2
Summary
InnateDB Gene IDBG-202091.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Flot2
Gene Name flotillin 2
Synonyms AI573412; Esa; reggie-2;
Species Mus musculus
Ensembl Gene ENSMUSG00000061981
Encoded Proteins
flotillin 2
flotillin 2
flotillin 2
flotillin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132589:
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:78037931-78060434
Strand Forward strand
Band B5
Transcripts
ENSMUST00000073660 ENSMUSP00000073342
ENSMUST00000072289 ENSMUSP00000072136
ENSMUST00000100784 ENSMUSP00000098347
ENSMUST00000148162 ENSMUSP00000133147
ENSMUST00000136353
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 34 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002020 protease binding
GO:0005515 protein binding
GO:0035255 ionotropic glutamate receptor binding
Biological Process
GO:0007155 cell adhesion
GO:0010629 negative regulation of gene expression
GO:0050821 protein stabilization
GO:0090002 establishment of protein localization to plasma membrane
GO:1902992 negative regulation of amyloid precursor protein catabolic process
Cellular Component
GO:0002080 acrosomal membrane
GO:0005768 endosome
GO:0005901 caveola
GO:0016020 membrane
GO:0016600 flotillin complex
GO:0030139 endocytic vesicle
GO:0031982 vesicle
GO:0045121 membrane raft
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
Insulin signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
EGFR1 pathway
REACTOME
KEGG
Insulin signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
p73 transcription factor network
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.130227
RefSeq NM_001040403 NM_001284228 NM_008028 XM_006532191 XM_006532192 XM_006532193 XM_006532194
OMIM
CCDS CCDS25088 CCDS36237
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas