InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Lat2

Summary

InnateDB Gene

IDBG-202957.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lat2

Gene Name

linker for activation of T cells family, member 2

Synonyms

AW125574; LAB; NTAL; Wbscr15; Wbscr5; WSCR5

Species

Mus musculus

Ensembl Gene

ENSMUSG00000040751

Encoded Proteins

IDBP-202959

linker for activation of T cells family, member 2

IDBP-202961

linker for activation of T cells family, member 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086730:
This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:134600268-134615023

Strand

Reverse strand

Band

Transcripts

ENSMUST00000036362	ENSMUSP00000046900
ENSMUST00000077636	ENSMUSP00000076824

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042169	SH2 domain binding

Biological Process

GO:0019722	calcium-mediated signaling
GO:0035556	intracellular signal transduction
GO:0042113	B cell activation
GO:0043303	mast cell degranulation
GO:0050853	B cell receptor signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0042629	mast cell granule
GO:0045121	membrane raft
GO:0070062	extracellular vesicular exosome