InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Adss

Summary

InnateDB Gene

IDBG-206767.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adss

Gene Name

adenylosuccinate synthetase, non muscle

Synonyms

Adss2; AI314886; AS

Species

Mus musculus

Ensembl Gene

ENSMUSG00000015961

Encoded Proteins

IDBP-206769

adenylosuccinate synthetase, non muscle

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000035687:
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:177762962-177796511

Strand

Reverse strand

Band

Transcripts

ENSMUST00000016105	ENSMUSP00000016105
ENSMUST00000159184
ENSMUST00000161808

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004019	adenylosuccinate synthase activity
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0006164	purine nucleotide biosynthetic process
GO:0006167	AMP biosynthetic process
GO:0006184	GTP catabolic process
GO:0006531	aspartate metabolic process
GO:0014074	response to purine-containing compound
GO:0044208	'de novo' AMP biosynthetic process
GO:0046040	IMP metabolic process
GO:0060359	response to ammonium ion
GO:0071257	cellular response to electrical stimulus