Version 5.4
Bos taurus Gene: ADSS
Summary
InnateDB Gene IDBG-631352.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADSS
Gene Name Adenylosuccinate synthetase isozyme 2
Synonyms ADSS2; AMPASE2
Species Bos taurus
Ensembl Gene ENSBTAG00000013885
Encoded Proteins
IDBP-682886
Adenylosuccinate synthetase isozyme 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000035687:
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:33528215-33561117
Strand Forward strand
Band
Transcripts
ENSBTAT00000047061 ENSBTAP00000044296
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004019 adenylosuccinate synthase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006167 AMP biosynthetic process
GO:0044208 'de novo' AMP biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000035687
View Gene Order
ENSMUSG00000015961
View Gene Order
Pathways
NETPATH
REACTOME
REACT_210940
Metabolism of nucleotides pathway
REACT_205922
Purine metabolism pathway
REACT_219139
Metabolism pathway
REACT_226478
Purine ribonucleoside monophosphate biosynthesis pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1776
Purine ribonucleoside monophosphate biosynthesis pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_111217
Metabolism pathway
REACT_263730
Purine metabolism pathway
REACT_188937
Metabolism pathway
REACT_263184
Purine ribonucleoside monophosphate biosynthesis pathway
REACT_245662
Metabolism of nucleotides pathway
KEGG
hsa00230
Purine metabolism pathway
hsa00250
Alanine, aspartate and glutamate metabolism pathway
mmu00230
Purine metabolism pathway
mmu00250
Alanine, aspartate and glutamate metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Alanine Aspartate Asparagine metabolism pathway
PID NCI
Cross-References
SwissProt A7MBG0
TrEMBL Q6PWM0
UniProt Splice Variant
Entrez Gene 522529
UniGene Bt.24907 Bt.69452
RefSeq NM_001167809 XM_005216819
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY573611 BC151541
GenPept AAI51542 AAS86203
RNA Seq Atlas 522529

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca