Mus musculus Gene: Echs1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-211665.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Echs1 | ||||||||||||||||||||||
Gene Name | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | ||||||||||||||||||||||
Synonyms | C80529 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000025465 | ||||||||||||||||||||||
Encoded Proteins |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127884:
The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 7:140105710-140116476 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | F4 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Mitochondrial Fatty Acid Beta-Oxidation pathway
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA pathway
Metabolism pathway
Beta oxidation of octanoyl-CoA to hexanoyl-CoA pathway
Metabolism of lipids and lipoproteins pathway
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA pathway
mitochondrial fatty acid beta-oxidation of saturated fatty acids pathway
Beta oxidation of hexanoyl-CoA to butanoyl-CoA pathway
Beta oxidation of butanoyl-CoA to acetyl-CoA pathway
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KEGG |
beta-Alanine metabolism pathway
Valine, leucine and isoleucine degradation pathway
Fatty acid elongation pathway
Lysine degradation pathway
Tryptophan metabolism pathway
Propanoate metabolism pathway
Butanoate metabolism pathway
Fatty acid degradation pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Beta oxidation of hexanoyl-CoA to butanoyl-CoA pathway
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA pathway
Beta oxidation of butanoyl-CoA to acetyl-CoA pathway
Beta oxidation of octanoyl-CoA to hexanoyl-CoA pathway
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Mitochondrial Fatty Acid Beta-Oxidation pathway
mitochondrial fatty acid beta-oxidation of saturated fatty acids pathway
Metabolism pathway
Beta oxidation of butanoyl-CoA to acetyl-CoA pathway
Mitochondrial Fatty Acid Beta-Oxidation pathway
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA pathway
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA pathway
Metabolism of lipids and lipoproteins pathway
Beta oxidation of hexanoyl-CoA to butanoyl-CoA pathway
Metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Beta oxidation of octanoyl-CoA to hexanoyl-CoA pathway
mitochondrial fatty acid beta-oxidation of saturated fatty acids pathway
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KEGG |
Valine, leucine and isoleucine degradation pathway
Butanoate metabolism pathway
Propanoate metabolism pathway
Tryptophan metabolism pathway
Fatty acid degradation pathway
Fatty acid elongation pathway
Lysine degradation pathway
beta-Alanine metabolism pathway
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INOH |
Tryptophan degradation pathway
Propanoate metabolism pathway
Butanoate metabolism pathway
Valine Leucine Isoleucine degradation pathway
Lysine degradation pathway
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PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | Q8BH95 | ||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 93747 | ||||||||||||||||||||||
UniGene | Mm.24452 Mm.402648 Mm.408900 | ||||||||||||||||||||||
RefSeq | NM_053119 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS21964 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:2136460 | ||||||||||||||||||||||
MGI Symbol | Echs1 | ||||||||||||||||||||||
EMBL | AK040391 AK044954 AK088018 AK167404 BC002178 BC057971 BC072658 | ||||||||||||||||||||||
GenPept | AAH02178 AAH57971 AAH72658 BAC30583 BAC32157 BAC40099 BAE39493 | ||||||||||||||||||||||
RNA Seq Atlas | 93747 | ||||||||||||||||||||||