Version 5.4
| Homo sapiens Gene: RGS20 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-21786.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | RGS20 | ||||||||||||||||||
| Gene Name | regulator of G-protein signaling 20 | ||||||||||||||||||
| Synonyms | g(z)GAP; gz-GAP; RGSZ1; ZGAP1 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000147509 | ||||||||||||||||||
| Encoded Proteins |
regulator of G-protein signaling 20
regulator of G-protein signaling 20
regulator of G-protein signaling 20
regulator of G-protein signaling 20
regulator of G-protein signaling 20
regulator of G-protein signaling 20
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 8:53851808-53959303 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q11.23 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
G alpha (i) signalling events pathway
G alpha (z) signalling events pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
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| KEGG | |||||||||||||||||||
| INOH |
GPCR signaling pathway
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| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | O76081 | ||||||||||||||||||
| TrEMBL | B3KSW4 H9NIM5 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 8601 | ||||||||||||||||||
| UniGene | Hs.368733 Hs.741492 | ||||||||||||||||||
| RefSeq | NM_003702 NM_001286673 NM_001286674 NM_001286675 NM_170587 | ||||||||||||||||||
| HUGO | HGNC:14600 | ||||||||||||||||||
| OMIM | 607193 | ||||||||||||||||||
| CCDS | CCDS6156 CCDS6155 CCDS69482 | ||||||||||||||||||
| HPRD | 06225 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC100821 AC113194 AF060877 AF074979 AF366054 AF366055 AF366056 AF366057 AF493940 AK094503 AY046538 BC015614 BC063490 CH471068 JQ308180 | ||||||||||||||||||
| GenPept | AAC62009 AAC62013 AAH15614 AAH63490 AAK54122 AAK54123 AAK54124 AAK54125 AAL03971 AAM12654 AFF59490 BAG52876 EAW86738 | ||||||||||||||||||
| RNA Seq Atlas | 8601 | ||||||||||||||||||