Version 5.4
Homo sapiens Gene: TRIM71
Summary
InnateDB Gene IDBG-23894.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM71
Gene Name tripartite motif containing 71, E3 ubiquitin protein ligase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000206557
Encoded Proteins
IDBP-23896
tripartite motif containing 71
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23438823
TRIM71 was identified in a systematic screen for positive regulators of innate immune responses.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:32818018-32897826
Strand Forward strand
Band p22.3
Transcripts
ENST00000383763 ENSP00000373272
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0035198 miRNA binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0001843 neural tube closure
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010586 miRNA metabolic process
GO:0021915 neural tube development
GO:0035278 negative regulation of translation involved in gene silencing by miRNA
GO:0045087 innate immune response (InnateDB)
GO:0051246 regulation of protein metabolic process
GO:0051865 protein autoubiquitination
GO:0060964 regulation of gene silencing by miRNA
GO:0071310 cellular response to organic substance
GO:0072089 stem cell proliferation
GO:2000177 regulation of neural precursor cell proliferation
GO:2000637 positive regulation of gene silencing by miRNA
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005622 intracellular
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000079259
View Gene Order
ENSBTAG00000022744
Not yet available
Cross-References
SwissProt Q2Q1W2
TrEMBL
UniProt Splice Variant
Entrez Gene 131405
UniGene Hs.567678 Hs.598720
RefSeq NM_001039111
HUGO HGNC:32669
OMIM
CCDS CCDS43060
HPRD
IMGT
EMBL DQ232881
GenPept ABB18374
RNA Seq Atlas 131405

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca