Version 5.4
Homo sapiens Gene: GMPR2
Summary
InnateDB Gene IDBG-3727.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GMPR2
Gene Name guanosine monophosphate reductase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100938
Encoded Proteins
IDBP-3729
guanosine monophosphate reductase 2
IDBP-3731
guanosine monophosphate reductase 2
IDBP-230434
guanosine monophosphate reductase 2
IDBP-364035
guanosine monophosphate reductase 2
IDBP-364038
guanosine monophosphate reductase 2
IDBP-586128
guanosine monophosphate reductase 2
IDBP-587397
guanosine monophosphate reductase 2
IDBP-585784
guanosine monophosphate reductase 2
IDBP-596738
guanosine monophosphate reductase 2
IDBP-601409
guanosine monophosphate reductase 2
IDBP-591940
guanosine monophosphate reductase 2
IDBP-585583
guanosine monophosphate reductase 2
IDBP-593664
guanosine monophosphate reductase 2
IDBP-596753
guanosine monophosphate reductase 2
IDBP-592590
guanosine monophosphate reductase 2
IDBP-588358
guanosine monophosphate reductase 2
IDBP-600544
guanosine monophosphate reductase 2
IDBP-596002
guanosine monophosphate reductase 2
IDBP-597017
guanosine monophosphate reductase 2
IDBP-594382
guanosine monophosphate reductase 2
IDBP-600707
guanosine monophosphate reductase 2
IDBP-597845
guanosine monophosphate reductase 2
IDBP-595560
guanosine monophosphate reductase 2
IDBP-603018
guanosine monophosphate reductase 2
IDBP-604035
guanosine monophosphate reductase 2
IDBP-810270
guanosine monophosphate reductase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:24232422-24239242
Strand Forward strand
Band q12
Transcripts
ENST00000348719 ENSP00000334409
ENST00000355299 ENSP00000347449
ENST00000399440 ENSP00000382369
ENST00000420554 ENSP00000392859
ENST00000456667 ENSP00000405743
ENST00000559836 ENSP00000453299
ENST00000561038 ENSP00000452670
ENST00000559287 ENSP00000453594
ENST00000560139 ENSP00000453714
ENST00000559910 ENSP00000453537
ENST00000559801
ENST00000561035 ENSP00000454009
ENST00000559409 ENSP00000453761
ENST00000558865 ENSP00000454138
ENST00000558279 ENSP00000453079
ENST00000558701
ENST00000561130 ENSP00000453560
ENST00000558760 ENSP00000452840
ENST00000559102 ENSP00000453895
ENST00000557854 ENSP00000454038
ENST00000559104 ENSP00000453355
ENST00000559606
ENST00000558483 ENSP00000453139
ENST00000560517
ENST00000559943 ENSP00000452766
ENST00000558007
ENST00000558748 ENSP00000452683
ENST00000559479 ENSP00000452617
ENST00000558932 ENSP00000453833
ENST00000558788 ENSP00000453772
ENST00000620807 ENSP00000480342
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003920 GMP reductase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0008152 metabolic process
GO:0009117 nucleotide metabolic process
GO:0043101 purine-containing compound salvage
GO:0044281 small molecule metabolic process
GO:0046037 GMP metabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005829 cytosol
GO:1902560 GMP reductase complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_1923
Purine salvage pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.368855
RefSeq NM_001002000 NM_001002001 NM_001002002 NM_001283021 NM_001283022 NM_001283023 NM_016576 XM_005267742 XM_006720165
HUGO
OMIM
CCDS CCDS41935 CCDS45087 CCDS61419 CCDS73624
HPRD 13590
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca