Version 5.4
Homo sapiens Gene: SCLT1
Summary
InnateDB Gene IDBG-37917.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCLT1
Gene Name sodium channel and clathrin linker 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000151466
Encoded Proteins
IDBP-37919
sodium channel and clathrin linker 1
IDBP-377686
sodium channel and clathrin linker 1
IDBP-474476
sodium channel and clathrin linker 1
IDBP-479959
sodium channel and clathrin linker 1
IDBP-477878
sodium channel and clathrin linker 1
IDBP-476843
sodium channel and clathrin linker 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SCLT1 acts as a linker protein between the voltage-gated sodium channel Na(v)1.8 (SCN10A; MIM 604427) and clathrin (see CLTC, MIM 118955) (Liu et al., 2005 [PubMed 15797711]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:128864921-129093607
Strand Reverse strand
Band q28.2
Transcripts
ENST00000281142 ENSP00000281142
ENST00000439369 ENSP00000395292
ENST00000503565
ENST00000506233
ENST00000503215 ENSP00000424029
ENST00000502495
ENST00000506368 ENSP00000424304
ENST00000511426 ENSP00000420861
ENST00000503401 ENSP00000425315
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008022 protein C-terminus binding
GO:0017080 sodium channel regulator activity
GO:0030276 clathrin binding
Biological Process
GO:0042384 cilium assembly
GO:0045162 clustering of voltage-gated sodium channels
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0015630 microtubule cytoskeleton
GO:0070062 extracellular vesicular exosome
GO:0071439 clathrin complex
GO:0097539 ciliary transition fiber
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059834
View Gene Order
ENSBTAG00000013611
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.654690
RefSeq NM_001300897 NM_001300898 NM_144643 XM_005262732
HUGO
OMIM
CCDS CCDS3740
HPRD 08700
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca