Homo sapiens Gene: VPS54
Summary
InnateDB Gene IDBG-53799.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VPS54
Gene Name vacuolar protein sorting 54 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143952
Encoded Proteins
vacuolar protein sorting 54 homolog (S. cerevisiae)
vacuolar protein sorting 54 homolog (S. cerevisiae)
vacuolar protein sorting 54 homolog (S. cerevisiae)
vacuolar protein sorting 54 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:63892146-64019072
Strand Reverse strand
Band p14
Transcripts
ENST00000272322 ENSP00000272322
ENST00000354504 ENSP00000346499
ENST00000409558 ENSP00000386980
ENST00000416400 ENSP00000414725
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0040007 growth
GO:0042147 retrograde transport, endosome to Golgi
GO:0048873 homeostasis of number of cells within a tissue
GO:0050881 musculoskeletal movement
GO:0060052 neurofilament cytoskeleton organization
Cellular Component
GO:0000938 GARP complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9P1Q0
TrEMBL
UniProt Splice Variant
Entrez Gene 51542
UniGene
RefSeq NM_016516 NM_001005739
HUGO HGNC:18652
OMIM 614633
CCDS CCDS33208 CCDS46302
HPRD 10302
IMGT
EMBL AF102177 AK002205 AL137604 AL359939 AY444798 BC030275 BC041868 CR749701
GenPept AAF37319 AAH30275 AAH41868 AAS20945 BAA92134 CAB70837 CAB95772 CAH18479
RNA Seq Atlas 51542