Version 5.4
Homo sapiens Gene: RBM10
Summary
InnateDB Gene IDBG-59674.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBM10
Gene Name RNA binding motif protein 10
Synonyms DXS8237E; GPATC9; GPATCH9; S1-1; TARPS; ZRANB5
Species Homo sapiens
Ensembl Gene ENSG00000182872
Encoded Proteins
IDBP-59676
RNA binding motif protein 10
IDBP-59678
RNA binding motif protein 10
IDBP-59680
RNA binding motif protein 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:47144869-47186813
Strand Forward strand
Band p11.3
Transcripts
ENST00000377604 ENSP00000366829
ENST00000329236 ENSP00000328848
ENST00000345781 ENSP00000329659
ENST00000496012
ENST00000478410
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 80 [view]
Protein-Protein 80 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0032403 protein complex binding
GO:0042802 identical protein binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006397 mRNA processing
GO:0008150 biological_process
GO:0008285 negative regulation of cell proliferation
GO:0008380 RNA splicing
GO:0034391 regulation of smooth muscle cell apoptotic process
GO:0034393 positive regulation of smooth muscle cell apoptotic process
GO:0070935 3'-UTR-mediated mRNA stabilization
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031060
View Gene Order
ENSBTAG00000002890
Not yet available
Cross-References
SwissProt P98175
TrEMBL
UniProt Splice Variant
Entrez Gene 8241
UniGene Hs.401509 Hs.675736
RefSeq NM_001204466 NM_152856 XM_005272678 XM_005272679 XM_006724563 NM_001204467 NM_001204468 NM_005676 XM_005272677
HUGO HGNC:9896
OMIM 300080
CCDS CCDS56600 CCDS14274 CCDS75969
HPRD 02095
IMGT
EMBL AK292758 AL137421 AL513366 BC003089 BC004181 BC008733 BC024153 CH471164 D50912 U35373
GenPept AAB33572 AAH03089 AAH04181 AAH08733 AAH24153 BAA09471 BAF85447 CAB70731 CAI41700 EAW59283 EAW59284 EAW59285 EAW59287
RNA Seq Atlas 8241

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca