InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: GLUL

Summary

InnateDB Gene

IDBG-637016.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GLUL

Gene Name

Glutamine synthetase

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013631

Encoded Proteins

IDBP-688996

Glutamine synthetase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135821:
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:64948332-64958885

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000038488

ENSBTAP00000038301

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003824	catalytic activity
GO:0004351	glutamate decarboxylase activity
GO:0004356	glutamate-ammonia ligase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016829	lyase activity
GO:0016874	ligase activity
GO:0042802	identical protein binding

Biological Process

GO:0006542	glutamine biosynthetic process
GO:0006807	nitrogen compound metabolic process
GO:0008152	metabolic process
GO:0008283	cell proliferation
GO:0009267	cellular response to starvation
GO:0009749	response to glucose

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0044297	cell body
GO:0070062	extracellular vesicular exosome
GO:0097386	glial cell projection