Bos taurus Gene: SAT1
Summary
InnateDB Gene IDBG-638429.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SAT1
Gene Name Diamine acetyltransferase 1
Synonyms SAT
Species Bos taurus
Ensembl Gene ENSBTAG00000017363
Encoded Proteins
Diamine acetyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130066:
The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:126467442-126470489
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023087 ENSBTAP00000023087
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 54 interaction(s) predicted by orthology.
Predicted by orthology
Total 54 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004145 diamine N-acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0001525 angiogenesis
GO:0008152 metabolic process
GO:0009447 putrescine catabolic process
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Metabolism of amino acids and derivatives pathway
Interconversion of polyamines pathway
Metabolism pathway
Metabolism of polyamines pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Interconversion of polyamines pathway
Metabolism of polyamines pathway
Metabolism of amino acids and derivatives pathway
Metabolism pathway
Metabolism pathway
Metabolism of amino acids and derivatives pathway
Metabolism of polyamines pathway
Interconversion of polyamines pathway
KEGG
Arginine and proline metabolism pathway
Arginine and proline metabolism pathway
INOH
Arginine Proline metabolism pathway
PID NCI
Alpha9 beta1 integrin signaling events
Cross-References
SwissProt Q3T0Q0
TrEMBL F7VJJ0
UniProt Splice Variant
Entrez Gene 508861
UniGene Bt.97768
RefSeq NM_001034333
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102304 BK001352
GenPept AAI02305 DAA34836
RNA Seq Atlas 508861