Version 5.4
Bos taurus Gene: NPPC
Summary
InnateDB Gene IDBG-644450.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPPC
Gene Name C-type natriuretic peptide CNP-22 CNP-29 CNP-53
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003253
Encoded Proteins
IDBP-697090
C-type natriuretic peptideCNP-22CNP-29CNP-53
IDBP-697091
C-type natriuretic peptideCNP-22CNP-29CNP-53
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163273:
The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:120392634-120397261
Strand Reverse strand
Band
Transcripts
ENSBTAT00000043384 ENSBTAP00000040960
ENSBTAT00000063429 ENSBTAP00000055472
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005179 hormone activity
Biological Process
GO:0001503 ossification
GO:0003418 growth plate cartilage chondrocyte differentiation
GO:0003419 growth plate cartilage chondrocyte proliferation
GO:0006182 cGMP biosynthetic process
GO:0007168 receptor guanylyl cyclase signaling pathway
GO:0009791 post-embryonic development
GO:0030814 regulation of cAMP metabolic process
GO:0030823 regulation of cGMP metabolic process
GO:0040014 regulation of multicellular organism growth
GO:0044702 single organism reproductive process
GO:0048513 organ development
GO:0050880 regulation of blood vessel size
GO:0051447 negative regulation of meiotic cell cycle
GO:1900194 negative regulation of oocyte maturation
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000163273
View Gene Order
ENSMUSG00000026241
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.4102
RefSeq NM_174125 XM_005202886
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca