Version 5.4
| Homo sapiens Gene: LIMS2 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-69173.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | LIMS2 | ||||||||||||||||||
| Gene Name | LIM and senescent cell antigen-like domains 2 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000072163 | ||||||||||||||||||
| Encoded Proteins |
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
LIM and senescent cell antigen-like domains 2
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 2:127638381-127681786 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q14.3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Cell-extracellular matrix interactions pathway
Cell-Cell communication pathway
Cell junction organization pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI |
Integrin-linked kinase signaling
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| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| UniGene | Hs.469881 Hs.688940 | ||||||||||||||||||
| RefSeq | NM_001136037 NM_001161403 NM_001161404 NM_001256542 NM_017980 XM_005263710 XM_006712627 | ||||||||||||||||||
| HUGO | |||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS2147 CCDS54394 CCDS54395 CCDS54396 CCDS58725 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||