Homo sapiens Gene: DHRS9 | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||
InnateDB Gene | IDBG-74381.6 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | DHRS9 | ||||||||||||||||
Gene Name | dehydrogenase/reductase (SDR family) member 9 | ||||||||||||||||
Synonyms | 3-alpha-HSD; 3ALPHA-HSD; RDH-E2; RDH-TBE; RDH15; RDHL; RDHTBE; RETSDR8; SDR9C4 | ||||||||||||||||
Species | Homo sapiens | ||||||||||||||||
Ensembl Gene | ENSG00000073737 | ||||||||||||||||
Encoded Proteins |
dehydrogenase/reductase (SDR family) member 9
dehydrogenase/reductase (SDR family) member 9
dehydrogenase/reductase (SDR family) member 9
dehydrogenase/reductase (SDR family) member 9
dehydrogenase/reductase (SDR family) member 9
dehydrogenase/reductase (SDR family) member 9
dehydrogenase/reductase (SDR family) member 9
dehydrogenase/reductase (SDR family) member 9
|
||||||||||||||||
Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
||||||||||||||||
Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 2:169064789-169096167 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | q31.1 | ||||||||||||||||
Transcripts | |||||||||||||||||
Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||||||||||
Gene Ontology | |||||||||||||||||
Molecular Function |
|
||||||||||||||||
Biological Process |
|
||||||||||||||||
Cellular Component |
|
||||||||||||||||
Orthologs | |||||||||||||||||
Species
Mus musculus
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||
Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
The canonical retinoid cycle in rods (twilight vision) pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
Disease pathway
|
||||||||||||||||
KEGG |
Retinol metabolism pathway
|
||||||||||||||||
INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | |||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | |||||||||||||||||
UniGene | |||||||||||||||||
RefSeq | NM_001142270 NM_001142271 NM_001289763 NM_005771 NM_199204 XM_005246230 | ||||||||||||||||
HUGO | |||||||||||||||||
OMIM | |||||||||||||||||
CCDS | CCDS2231 CCDS74600 | ||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | |||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | |||||||||||||||||