Homo sapiens Gene: C9orf3
Summary
InnateDB Gene IDBG-76959.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C9orf3
Gene Name chromosome 9 open reading frame 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148120
Encoded Proteins
chromosome 9 open reading frame 3
chromosome 9 open reading frame 3
chromosome 9 open reading frame 3
chromosome 9 open reading frame 3
chromosome 9 open reading frame 3
chromosome 9 open reading frame 3
chromosome 9 open reading frame 3
chromosome 9 open reading frame 3
chromosome 9 open reading frame 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. This protein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:94726701-95087218
Strand Forward strand
Band q22.32
Transcripts
ENST00000277198 ENSP00000277198
ENST00000297979 ENSP00000297979
ENST00000375315 ENSP00000364464
ENST00000427193 ENSP00000387736
ENST00000424143 ENSP00000402171
ENST00000428313 ENSP00000401854
ENST00000451893 ENSP00000411451
ENST00000445181 ENSP00000413927
ENST00000489318
ENST00000488186
ENST00000473778
ENST00000462125
ENST00000479161
ENST00000460573
ENST00000478603
ENST00000471978
ENST00000478473 ENSP00000431923
ENST00000496567
ENST00000463372
ENST00000482056
ENST00000489562
ENST00000468164
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0005488 binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0019370 leukotriene biosynthetic process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.434253 Hs.597950 Hs.680988
RefSeq NM_001193329 NM_001193331 NM_032823 XM_006717306 XM_006717307
HUGO
OMIM
CCDS CCDS55327 CCDS55328 CCDS6713
HPRD 07476
IMGT
EMBL
GenPept
RNA Seq Atlas