Version 5.4
Mus musculus Gene: Mtbp
Summary
InnateDB Gene IDBG-141711.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtbp
Gene Name Mdm2, transformed 3T3 cell double minute p53 binding protein
Synonyms AI429604; MDM2BP
Species Mus musculus
Ensembl Gene ENSMUSG00000022369
Encoded Proteins
IDBP-141713
Mdm2, transformed 3T3 cell double minute p53 binding protein
IDBP-627095
Mdm2, transformed 3T3 cell double minute p53 binding protein
IDBP-627096
Mdm2, transformed 3T3 cell double minute p53 binding protein
IDBP-627097
Mdm2, transformed 3T3 cell double minute p53 binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172167:
This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:55557408-55626423
Strand Forward strand
Band D1
Transcripts
ENSMUST00000022998 ENSMUSP00000022998
ENSMUST00000170046 ENSMUSP00000129396
ENSMUST00000169517 ENSMUSP00000131887
ENSMUST00000169667 ENSMUSP00000128615
ENSMUST00000171146
ENSMUST00000166449
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007050 cell cycle arrest
GO:0007089 traversing start control point of mitotic cell cycle
GO:0008285 negative regulation of cell proliferation
GO:0034501 protein localization to kinetochore
GO:0071174 mitotic spindle checkpoint
Cellular Component
GO:0000776 kinetochore
GO:0000785 chromatin
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000172167
View Gene Order
ENSBTAG00000006770
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.390829 Mm.484012
RefSeq NM_001168250 NM_134092 XM_006520250 XM_006520251
OMIM
CCDS CCDS27478 CCDS49609
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca