Version 5.4
Mus musculus Gene: Fgf13
Summary
InnateDB Gene IDBG-147880.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fgf13
Gene Name fibroblast growth factor 13
Synonyms Fhf2
Species Mus musculus
Ensembl Gene ENSMUSG00000031137
Encoded Proteins
IDBP-147884
fibroblast growth factor 13
IDBP-401135
fibroblast growth factor 13
IDBP-401133
fibroblast growth factor 13
IDBP-537674
fibroblast growth factor 13
IDBP-537201
fibroblast growth factor 13
IDBP-535199
fibroblast growth factor 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129682:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5\' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:59062145-59568071
Strand Reverse strand
Band A6
Transcripts
ENSMUST00000033473 ENSMUSP00000033473
ENSMUST00000119833 ENSMUSP00000113639
ENSMUST00000119306 ENSMUSP00000113206
ENSMUST00000138503
ENSMUST00000123660
ENSMUST00000124402 ENSMUSP00000114905
ENSMUST00000131319 ENSMUSP00000115765
ENSMUST00000145767 ENSMUSP00000119897
ENSMUST00000150413
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0008083 growth factor activity
GO:0017080 sodium channel regulator activity
GO:0030295 protein kinase activator activity
GO:0044325 ion channel binding
GO:0048487 beta-tubulin binding
Biological Process
GO:0000165 MAPK cascade
GO:0001764 neuron migration
GO:0007026 negative regulation of microtubule depolymerization
GO:0007612 learning
GO:0007613 memory
GO:0021766 hippocampus development
GO:0021795 cerebral cortex cell migration
GO:0045200 establishment of neuroblast polarity
GO:0045860 positive regulation of protein kinase activity
GO:0046785 microtubule polymerization
GO:0048671 negative regulation of collateral sprouting
GO:0072659 protein localization to plasma membrane
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0014704 intercalated disc
GO:0030175 filopodium
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0043005 neuron projection
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129682
View Gene Order
ENSBTAG00000020194
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05218
Melanoma pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu04010
MAPK signaling pathway pathway
mmu05200
Pathways in cancer pathway
INOH
INOH website
FGF signaling pathway pathway
INOH website
GPCR signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa04010
MAPK signaling pathway pathway
hsa05218
Melanoma pathway
hsa05200
Pathways in cancer pathway
INOH
INOH website
FGF signaling pathway pathway
INOH website
GPCR signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.7995
RefSeq NM_001290415 NM_010200 XM_006527797 XM_006527798 XM_006527799
OMIM
CCDS CCDS30157 CCDS72383
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca