Version 5.4
Mus musculus Gene: Ccdc109a
Summary
InnateDB Gene IDBG-153943.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccdc109a
Gene Name coiled-coil domain containing 109A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000009647
Encoded Proteins
IDBP-153945
coiled-coil domain containing 109A
IDBP-153947
coiled-coil domain containing 109A
IDBP-541201
coiled-coil domain containing 109A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156026:
This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:59446984-59616692
Strand Reverse strand
Band B4
Transcripts
ENSMUST00000020312 ENSMUSP00000020312
ENSMUST00000009791 ENSMUSP00000009791
ENSMUST00000161435 ENSMUSP00000124087
ENSMUST00000161168
ENSMUST00000162012
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005262 calcium channel activity
GO:0005515 protein binding
GO:0015292 uniporter activity
GO:0042802 identical protein binding
Biological Process
GO:0006851 mitochondrial calcium ion transport
GO:0019722 calcium-mediated signaling
GO:0032024 positive regulation of insulin secretion
GO:0035786 protein complex oligomerization
GO:0036444 calcium ion import into mitochondrion
GO:0042593 glucose homeostasis
GO:0051560 mitochondrial calcium ion homeostasis
GO:0051561 positive regulation of mitochondrial calcium ion concentration
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0031305 integral component of mitochondrial inner membrane
GO:0034704 calcium channel complex
GO:1990246 uniplex complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000156026
View Gene Order
ENSBTAG00000003876
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.296470 Mm.397150
RefSeq NM_001033259 XM_006513468
OMIM
CCDS CCDS23866
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca