Version 5.4
Bos taurus Gene: ARL2BP
Summary
InnateDB Gene IDBG-632446.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARL2BP
Gene Name ADP-ribosylation factor-like protein 2-binding protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004844
Encoded Proteins
IDBP-684058
ADP-ribosylation factor-like protein 2-binding protein
IDBP-684060
ADP-ribosylation factor-like protein 2-binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102931:
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:25334588-25339259
Strand Forward strand
Band
Transcripts
ENSBTAT00000006363 ENSBTAP00000006363
ENSBTAT00000046263 ENSBTAP00000043580
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0051457 maintenance of protein location in nucleus
GO:2001141 regulation of RNA biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005929 cilium
GO:0030496 midbody
GO:0042995 cell projection
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000102931
View Gene Order
ENSMUSG00000031776
View Gene Order
Cross-References
SwissProt Q32PC9
TrEMBL
UniProt Splice Variant
Entrez Gene 613462
UniGene Bt.11667
RefSeq NM_001076274 XM_005218708
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC108166 BC134728
GenPept AAI08167 AAI34729
RNA Seq Atlas 613462

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca