Homo sapiens Gene: SYTL2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-66497.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | SYTL2 | ||||||||||||||||||||||
Gene Name | synaptotagmin-like 2 | ||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000137501 | ||||||||||||||||||||||
Encoded Proteins |
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
synaptotagmin-like 2
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jun 2009] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 11:85694224-85811159 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | q14.1 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | E9PK22 E9PS39 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 54843 | ||||||||||||||||||||||
UniGene | Hs.369520 Hs.596233 | ||||||||||||||||||||||
RefSeq | NM_001162951 NM_001162952 NM_001162953 NM_001289608 NM_001289609 NM_001289610 NM_032379 NM_032943 NM_206929 NM_206930 XM_005274060 XM_005274061 XM_005274063 XM_005274067 XM_006718590 | ||||||||||||||||||||||
HUGO | HGNC:15585 | ||||||||||||||||||||||
OMIM | 612880 | ||||||||||||||||||||||
CCDS | CCDS31649 CCDS31652 CCDS41698 CCDS53687 CCDS53688 CCDS53689 | ||||||||||||||||||||||
HPRD | 10260 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | AP000642 AP000974 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 54843 | ||||||||||||||||||||||