Version 5.4
| Homo sapiens Gene: FBLIM1 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-91122.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | FBLIM1 | ||||||||||||||||||
| Gene Name | filamin binding LIM protein 1 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000162458 | ||||||||||||||||||
| Encoded Proteins |
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
filamin binding LIM protein 1
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 1:15756607-15786594 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | p36.21 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Cell-extracellular matrix interactions pathway
Cell-Cell communication pathway
Cell junction organization pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | D6R9I4 D6R9V9 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 54751 | ||||||||||||||||||
| UniGene | Hs.530101 Hs.739205 | ||||||||||||||||||
| RefSeq | NM_001024215 NM_001024216 NM_017556 XM_005245900 XM_005245901 XM_005245902 XM_005245903 XM_005245904 XM_005245908 XM_005245909 XM_005245911 XM_006710704 XM_006710705 | ||||||||||||||||||
| HUGO | HGNC:24686 | ||||||||||||||||||
| OMIM | 607747 | ||||||||||||||||||
| CCDS | CCDS163 CCDS30609 CCDS44064 | ||||||||||||||||||
| HPRD | 09669 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AL450998 | ||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 54751 | ||||||||||||||||||