Homo sapiens Gene: IMMP2L
Summary
InnateDB Gene IDBG-36525.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMMP2L
Gene Name IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184903
Encoded Proteins
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:110663051-111562517
Strand Reverse strand
Band q31.1
Transcripts
ENST00000331762 ENSP00000329553
ENST00000405709 ENSP00000384966
ENST00000452895 ENSP00000399353
ENST00000450877 ENSP00000402824
ENST00000447215 ENSP00000388327
ENST00000437687 ENSP00000394387
ENST00000452753 ENSP00000407402
ENST00000487733
ENST00000489381
ENST00000492938
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0001541 ovarian follicle development
GO:0006508 proteolysis
GO:0006627 protein processing involved in protein targeting to mitochondrion
GO:0007283 spermatogenesis
GO:0030728 ovulation
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042720 mitochondrial inner membrane peptidase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Protein export pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q96T52
TrEMBL A4D0S9 C9JVB0
UniProt Splice Variant
Entrez Gene 83943
UniGene Hs.655722 Hs.683461 Hs.731706
RefSeq NM_001244606 NM_032549 XM_005250632
HUGO HGNC:14598
OMIM 605977
CCDS CCDS5753
HPRD 07297
IMGT
EMBL AC003989 AC004142 AC005161 AC005166 AC006002 AC006392 AC006993 AC006997 AC073326 AC073980 AC092613 AC106866 AF359563 AK311968 BC008497 CH236947 CH471070
GenPept AAH08497 AAK52905 AAS02043 AAS07432 AAS07496 AAS07497 AAS07528 BAG34907 EAL24378 EAW83444 EAW83446 EAW83447
RNA Seq Atlas 83943