Homo sapiens Gene: PIP5K1B
Summary
InnateDB Gene IDBG-69048.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIP5K1B
Gene Name phosphatidylinositol-4-phosphate 5-kinase, type I, beta
Synonyms MSS4; STM7;
Species Homo sapiens
Ensembl Gene ENSG00000107242
Encoded Proteins
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:68705414-69009176
Strand Forward strand
Band q21.11
Transcripts
ENST00000265382 ENSP00000265382
ENST00000377284 ENSP00000366498
ENST00000437200 ENSP00000398587
ENST00000440050 ENSP00000411477
ENST00000472907
ENST00000474356
ENST00000478500 ENSP00000435778
ENST00000541509 ENSP00000438082
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016307 phosphatidylinositol phosphate kinase activity
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006661 phosphatidylinositol biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046488 phosphatidylinositol metabolic process
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0001931 uropod
GO:0005829 cytosol
GO:0012505 endomembrane system
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
Wnt pathway
BCR pathway
REACTOME
WNT mediated activation of DVL pathway
Metabolism of lipids and lipoproteins pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Signaling by WNT in cancer pathway
Synthesis of PIPs at the plasma membrane pathway
Signaling by Wnt pathway
Signal Transduction pathway
TCF dependent signaling in response to WNT pathway
PI Metabolism pathway
Phospholipid metabolism pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
Metabolism pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
Disease pathway
KEGG
Inositol phosphate metabolism pathway
Phosphatidylinositol signaling system pathway
Endocytosis pathway
Fc gamma R-mediated phagocytosis pathway
Regulation of actin cytoskeleton pathway
INOH
Inositol phosphate metabolism pathway
PID BIOCARTA
Rho cell motility signaling pathway [Biocarta view]
PID NCI
Plexin-D1 Signaling
RAC1 signaling pathway
Canonical Wnt signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.534371
RefSeq NM_001278253 NM_003558 XM_005252261 XM_005252262 XM_006717300 XM_006717301
HUGO
OMIM
CCDS CCDS65063 CCDS6624
HPRD 04121
IMGT
EMBL
GenPept
RNA Seq Atlas